Discover groundbreaking research on the analgesic effects of endocannabinoids 2-AG, 2-PG, and 2-LG on TRPV1 receptors in cultured DRG neurons. This study provides invaluable insights into pain management and suggests novel avenues for drug development.
Researchers conducted a systematic review of studies investigating the use of cannabinoid-based medicines (CBMs) for chronic pain management and developed clinical practice guidelines based on the evidence. The review found that CBMs may provide benefits for chronic pain reduction, especially for neuropathic pain, and help with some co-occurring conditions. However, CBMs may cause some adverse events, and the optimal use of CBMs for chronic pain and co-occurring conditions is not clear. The guidelines provide practical recommendations for clinicians on patient education, assessment, dosing, administration routes, monitoring, and discontinuation of CBMs.
Dive into the world of medical cannabis from a Swedish physician’s perspective. Dr. Orzala Pazhman shares her insights on treating chronic pain with cannabis-based medicines and discusses the future of medical cannabis in Sweden.