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Explore the intricate bidirectional relationship between the Endocannabinoid System (ECS) and Peroxisome Proliferator-Activated Receptor Gamma (PPARγ). This comprehensive review delves into their roles in metabolic and inflammatory regulation, molecular interactions, and emerging therapeutic possibilities.
Explore the intricate interplay between dietary omega fatty acids and the Homeostatic System, and its implications for health and disease. Delve into how molecular pharmacology meets nutritional science to unfold promising avenues for disease prevention and management.
Investigating the synergistic effects of cannabinoids 331-18A, CBDV, and CBD, this groundbreaking study targets NOTCH1-Mutated T-Cell Lymphoblastic Acute Leukemia (T-ALL) through the Integrated Stress Response Pathway. By exploring the ‘entourage effect’ with a combination of specific phytocannabinoids, the research opens up new therapeutic horizons, shedding light on the intricate molecular interactions and their potential in cancer treatment.
This article explores the role of nanotechnology in improving the delivery and efficacy of cannabinoids. By focusing on nanoencapsulation techniques such as liposomes and polymeric nanoparticles, we delve into how these methods can enhance bioavailability, stability, and therapeutic efficacy of cannabinoids, thereby offering significant advancements in molecular pharmacology.
In the groundbreaking study “Postsynaptic Synucleins Mediate Endocannabinoid Signaling,” Eddy Albarran and colleagues delve into the intricate dance between synucleins and endocannabinoids within postsynaptic neurons. Their findings shed light on the potential role of phytocannabinoids in alleviating symptoms of Parkinson’s disease, offering a fresh perspective on therapeutic strategies
Celebrating the life and legacy of Dr. Raphael Mechoulam, a pioneering scientist in the fields of molecular pharmacology and cannabinoid research. His groundbreaking work on the endocannabinoid system (ECS) has transformed our understanding of human physiology and medical science.