# Aurea Care Medical Science Journal

> Scientific magazine with a focus on medical cannabis

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## Pages

- [Patient stories](https://aureamedicalsciencejournal.se/patient-stories/): This is an online scientific journal targeted towards the healthcare sector about the science of medical cannabis and the physiology of the endocannabinoid system.
- [Multimedia](https://aureamedicalsciencejournal.se/multimedia/): This is an online scientific journal targeted towards the healthcare sector about the science of medical cannabis and the physiology of the endocannabinoid system.
- [Scientific Studies](https://aureamedicalsciencejournal.se/scientific-studies/): Sweden's first scientific magazine with a focus on everything about medical cannabis.
- [Opinion pieces](https://aureamedicalsciencejournal.se/opinion-pieces/): Sweden's first scientific magazine with a focus on everything about medical cannabis.
- [Interviews with healthcare professionals working with Medical Cannabis](https://aureamedicalsciencejournal.se/interviews/): Sweden's first scientific magazine with a focus on everything about medical cannabis.
- [Key Opinion Leaders in Medical Cannabis](https://aureamedicalsciencejournal.se/key-opinion-leaders-in-medical-cannabis/): Sweden's first scientific magazine with a focus on everything about medical cannabis.
- [Educational Texts](https://aureamedicalsciencejournal.se/educational-texts/): Sweden's first scientific magazine with a focus on everything about medical cannabis.
- [About the Journal](https://aureamedicalsciencejournal.se/about-the-journal/): This is an online scientific journal targeted towards the healthcare sector about the science of medical cannabis and the physiology of the endocannabinoid system.
- [Home](https://aureamedicalsciencejournal.se/): Educational Texts Opinion pieces Scientific Studies Interviews with healthcare professionals working with Medical Cannabis Key Opinion Leaders in Medical Cannabis...
- [Privacy Policy](https://aureamedicalsciencejournal.se/privacy-policy/): Privacy Policy Aureum Life AB (also hereafter ‘we’) strives to ensure protection of your privacy when using our services. We...

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## Posts

- [What Stoners and Buddhists Understood Before Neuroscientists](https://aureamedicalsciencejournal.se/what-stoners-and-buddhists-understood-before-neuroscientists/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Centuries before neuroscience, the Buddhists looked inward and saw what...
- [The Philosopher's Plant](https://aureamedicalsciencejournal.se/the-philosophers-plant/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Time usually behaves. It ticks along, easy to ignore. Then...
- [What Cannabis Teaches Us About Reality](https://aureamedicalsciencejournal.se/what-cannabis-teaches-us-about-reality/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Reality is supposed to be solid. The ground under your...
- [The War on Consciousness](https://aureamedicalsciencejournal.se/the-war-on-consciousness/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Your consciousness is the only thing you’ve ever truly owned....
- [What Cannabis Tells Us About Medicine](https://aureamedicalsciencejournal.se/what-cannabis-tells-us-about-medicine/): Rules and Their Limits Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Modern medicine likes rules. One symptom....
- [Pain Is Not Just a Signal. It’s a Story.](https://aureamedicalsciencejournal.se/pain-is-not-just-a-signal-its-a-story/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Sitting was a timed event for him, though he didn’t...
- [Medical Cannabis and Polypharmacy: When Less Is More](https://aureamedicalsciencejournal.se/medical-cannabis-and-polypharmacy-when-less-is-more/): How cannabis can reduce medication burden Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Some patients don’t have...
- [CBD, THC, CBN, CBG, and the Alphabet Soup of Cannabinoids](https://aureamedicalsciencejournal.se/cbd-thc-cbn-cbg-and-the-alphabet-soup-of-cannabinoids/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Think of cannabis as a band. Most people only know...
- [The Case for Cannabis in Complex Conditions](https://aureamedicalsciencejournal.se/the-case-for-cannabis-in-complex-conditions/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Let’s talk about the patients who don’t fit in boxes....
- [The Endocannabinoid System](https://aureamedicalsciencejournal.se/the-endocannabinoid-system/): The Endo­cannabi­noid ­System: The Most Important System You’ve Never Heard Of Author: Dr. Kim, Medical Doctor at Aurea Care (Pen...
- [Cannabis Isn’t a Cure-All — But Here’s What It Does Really Well](https://aureamedicalsciencejournal.se/cannabis-isnt-a-cure-all-but-heres-what-it-does-really-well/): Author: Dr. Kim, Medical Doctor at Aurea Care (Pen name) Let’s get one thing straight: cannabis isn’t magic. It won’t...
- [The Role of Cannabinoids in SARS-CoV-2 Infection and COVID-19 Management](https://aureamedicalsciencejournal.se/the-role-of-cannabinoids-in-covid-19/): Explore the intersection of cannabinoids and COVID-19 management, shedding light on the antiviral, immunomodulatory, and neuroprotective potentials of cannabinoids against SARS-CoV-2. Delve into the clinical implications, risks, and future prospects as we navigate through existing research towards a more efficacious therapeutic paradigm in combating this global pandemic.
- [Shifting Sands of Perception: The Impact of Evidence-Based Education on Cannabis Attitudes in Sinaloa, Mexico](https://aureamedicalsciencejournal.se/shifting-sands-of-perception-the-impact-of-evidence-based-education-on-cannabis-attitudes-in-sinaloa-mexico/): Unveil the transformative impact of evidence-based education on public attitudes towards cannabis in Sinaloa, Mexico. Explore how demographic factors mediate the effectiveness of educational interventions and what this means for future drug policies. A must-read for anyone interested in the intersection of public health, policy, and social perceptions.
- [Unveiling the bidirectional regulation between the Endocannabinoid System and Peroxisome Proliferator-Activated Receptor Gamma](https://aureamedicalsciencejournal.se/ecs-ppargamma-bidirectional-regulation/): Dive deep into the symbiotic relationship between the Endocannabinoid System and PPARγ. Understand their roles in metabolism, inflammation, and potential as therapeutic targets. A must-read for healthcare professionals, pharmacologists, and researchers interested in metabolic and inflammatory disorders.
- [Omega Fatty Acids and the Homeostatic System: Molecular Interactions and Dietary Implications](https://aureamedicalsciencejournal.se/omega-fatty-acids-and-ecs/): Uncover the molecular dialogues between dietary omega fatty acids and the Homeostatic System. This comprehensive review highlights the pivotal role of omega fatty acids in modulating physiological processes, offering insights into potential therapeutic interventions and the importance of interdisciplinary collaboration in advancing nutritional therapeutics.
- [](https://aureamedicalsciencejournal.se/the-homeostatic-system-effects-on-physiology/): Dive into the intricate roles of the Endocannabinoid System (ECS) in regulating physiological homeostasis across diverse organ systems. Co-authored by two experts in the field, Stefan Broselid, Ph.D. and Sasha Weedowitch, BN, this article serves as an essential guide for healthcare providers, researchers, and educators, advocating for a more integrated ECS understanding in medical education and clinical practice.
- [Navigating the Complex Landscape of Medical Cannabis: A Conversation with Dr. Amal Hagos on Ethics, Evidence, and Patient Care](https://aureamedicalsciencejournal.se/interview-amal-hagos/): An enlightening discussion with Dr. Amal Hagos, a pain management specialist at Aurea Care in Stockholm, on the complexities and...
- [Exploring Autistic Spectrum Disorder through the lens of ECS dysfunction](https://aureamedicalsciencejournal.se/exploring-asd-and-ec-dysfunction/): Dive into an extensive review highlighting the intricate relationship between the Endocannabinoid System (ECS) and Autism Spectrum Disorders (ASD). Uncover key insights from in vivo models, clinical trials, and biomarker studies, shedding light on ECS dysfunction in ASD. This article aims to pave the way for future research and more effective, targeted treatments for ASD.
- [Synergistic Effects of Endocannabinoids in Neuropathic Pain Models: A Focus on TRPV1 Modulation](https://aureamedicalsciencejournal.se/ecb-entourage-trpv1/): Unpacking the study "The Endocannabinoid Analgesic Entourage Effect," this article delves into the analgesic potential of endocannabinoids 2-AG, 2-PG, and 2-LG. Learn how these lipid-based signaling molecules influence TRPV1 receptor activation and offer new prospects for chronic pain management.
- [A Breakdown of Solmi et al.'s BMJ Umbrella Review regarding harms and benefits of cannabis use](https://aureamedicalsciencejournal.se/bmj-umbrella-review/): Dive into a groundbreaking umbrella review comparing the risks and benefits of cannabis. Utilizing the GRADE framework, this article provides a multi-faceted analysis that could reshape both clinical guidelines and public policy. Includes a detailed chart visualizing GRADE certainty levels
- [Decoding the Symphony: Genetic Variations in the ECS and Their Impact on Health](https://aureamedicalsciencejournal.se/genetic-variations-in-ecs-impact-on-health/): "Decoding the Symphony: Genetic Variations in the ECS and Their Impact on Health" offers an in-depth analysis of the Endocannabinoid System's role in human physiology and its vulnerability to genetic mutations. The article provides an insightful look into how these genetic variations can influence behavior, disease prevalence, and pave the way for future therapeutic innovations. Ideal for healthcare professionals, researchers, and educators seeking a nuanced understanding of the ECS.
- [Three Phytocannabinoids Join Forces to Battle NOTCH1-Mutated T-Cell Lymphoblastic Acute Leukemia](https://aureamedicalsciencejournal.se/entourage-t-all/): Discover the pioneering work led by David “Dedi” Meiri that unveils the synergistic potential of three specific cannabinoids (331-18A, CBDV, and CBD) in battling NOTCH1-Mutated T-ALL. This comprehensive study, currently in preprint in BioRxIv, explores both in vitro and in vivo experiments to decode the 'entourage effect' in phytocannabinoids, laying a foundation for innovative cancer therapies and expanding our understanding of the Master Homeostatic Regulatory System (MHRS).
- [Dissecting the Acute Neurological Effects of THC: Insights from Resting State fMRI and Genetic Modulation](https://aureamedicalsciencejournal.se/thc-neurological-effects-genetics/): "Dissecting the Acute Neurological Effects of THC" provides a comprehensive analysis of THC's acute effects on the brain. Drawing from resting state fMRI and genetic modulation, the study reveals how THC alters the brain's functionality, especially in individuals with specific genetic makeups. The findings extend our understanding of the endocannabinoid system's role in mental and dopaminergic health, opening new avenues for research and potential therapeutic applications.
- [Global Insights: Physicians' Knowledge & Attitudes Towards Medical Cannabis](https://aureamedicalsciencejournal.se/international-physicians-perspective-medical-cannabis-2023-study/): Unpacking Syed et al.'s groundbreaking 2023 study on physicians' perspectives of medical cannabis. Explore international insights, knowledge gaps, and the call for a more informed medical community on the use and potential of cannabis in treatment.
- [Interview with Sasha Weedowitch, a mental nurse and clinical endocannabinologist](https://aureamedicalsciencejournal.se/endocannabinology-interview/): Discover the field of endocannabinology and its focus on the endocannabinoid system (ECS) for maintaining mental and physical health. Learn how the 'endocannabinology approach' differs from a 'medical cannabis approach'. Gain insights into integrating endocannabinology into mental health nursing. Read this insightful interview for a comprehensive understanding of endocannabinology.
- [Stockholm Medical Cannabis Conference: A Pivot Point Amidst Sweden's Escalating Drug Crisis](https://aureamedicalsciencejournal.se/smcc2023/): Join the pivotal conversation on medical cannabis at the Stockholm Medical Cannabis Conference. Explore diverse topics surrounding the potential benefits of cannabis, patient narratives, and the impact of shifting from punitive to harm reduction strategies. Be part of the solution in Sweden's escalating drug crisis.
- [Skin Salvation: Soothing, Healing, and Numbing with Topical Cannabinoids](https://aureamedicalsciencejournal.se/navigating-the-world-of-topical-cannabinoids/): Dive into the realm of topical cannabinoids and their applications in treating various skin conditions and managing pain. This in-depth review unravels the scientific evidence, market availability, regulatory status, and future prospects of these potent compounds. Equip yourself with the latest knowledge and stay at the forefront of this promising pharmacological field.
- [Cannabis Conundrum: Is the 'High' a Side Effect or a Separate Show?](https://aureamedicalsciencejournal.se/rethinking-cannabis-high-therapeutic-potential/): Dive into the world of medical cannabis and the controversial 'high' it induces. This article, grounded in recent research, challenges the notion that the 'high' is an unwanted side effect, suggesting instead that it may be a separate phenomenon that doesn't hinder the therapeutic potential of cannabis.
- [Improving cannabinoid posology through nanotechnology](https://aureamedicalsciencejournal.se/nanotechnology-enhanced-cannabinoid-delivery/): Unlock the potential of nanotechnology in revolutionizing cannabinoid delivery. Learn how nanoencapsulation can optimize pharmacokinetic and pharmacodynamic properties, mitigate challenges, and expand the therapeutic potential of cannabinoids. A must-read for anyone interested in the intersection of molecular pharmacology and nanotechnology.
- [Is CBD effective against more than indications than paediatric epilepsies? - What does the clinical evidence tell us?](https://aureamedicalsciencejournal.se/is-cbd-effective-against-more-than-epilepsy/): In this blog post, we provide a summary of a recent review article published in the Journal of Cannabis Research...
- [The Gut-Brain Axis and Its Influence Over Endocannabinoid Tone](https://aureamedicalsciencejournal.se/the-gut-brain-bliss-connection/): Delve into the captivating Gut-Brain-Bliss Connection and unravel the intricate relationship between the gut microbiota, endocannabinoid system, and overall well-being. Discover the potential implications for neurological disorders, mental health, and personalized therapeutic interventions. Explore the forefront of health research with this thought-provoking article.
- [Beyond the High: Unraveling Non-GPCR Targets in the eCBome](https://aureamedicalsciencejournal.se/non-gpcr-targets-in-the-ecbome/): Uncover the significant role of non-GPCR targets within the endocannabinoid system. With a keen focus on FAAH, MAGL, DAGL, NAPE-PLD, TRP channels, and PPARs, this comprehensive review provides insights into their implications in a spectrum of human pathologies, including neuropsychiatric, metabolic, and neurological disorders. A valuable resource for medical professionals and researchers alike.
- [Synuclein Synchrony: A Dance of Proteins and Endocannabinoids in Parkinson's Disease](https://aureamedicalsciencejournal.se/synuclein-synchrony/): Explore the fascinating interplay between synucleins and endocannabinoids in Parkinson's disease (PD). This article summarizes the key findings of a recent study published in Nature Neuroscience, offering insights into the potential therapeutic role of phytocannabinoids in PD. Dive into the world of molecular pharmacology and neuroscience as we unravel new findings related to Parkinson's disease.
- [Deciphering the eCBome Enigma: A Deep Dive into the GPCR Pool](https://aureamedicalsciencejournal.se/deciphering-the-ecbome-enigma/): Dive into the world of eCBome GPCRs with this comprehensive review. Discover the intricate roles of different receptors in the endocannabinoid system and their links to various diseases. Uncover the future potential of this fascinating area in therapeutic interventions and novel research directions. A must-read for anyone interested in neuroscience, pharmacology, and the future of personalised medicine.
- [Genetic Influencers: The Effects of Tobacco, Alcohol, and Cannabis on DNA Methylation](https://aureamedicalsciencejournal.se/tobacco-alcohol-cannabis-dna-methylation-effects-health/): Dive into the world of epigenetics and learn about the profound impact of substance use on DNA methylation. Explore a detailed study investigating the effects of tobacco, alcohol, and cannabis on our genetic 'algorithm'. Understand the implications of these findings on health outcomes and appreciate the need for further research in the field. Informed decisions today can lead to better health tomorrow.
- [Medical Cannabis and Quality of Life Improvement: A Review of the Arkell et al, 2023 Study in JAMA Network Open](https://aureamedicalsciencejournal.se/medical-cannabis-improves-quality-of-life-study-review/): This article reviews a study published in JAMA Network Open by Arkell et al., exploring the potential benefits of medical cannabis on health-related quality of life. Particularly, it suggests that medical cannabis may help improve quality of life for patients with chronic pain, with CBD-dominant products showing promising results.
- [Optimizing Your Endocannabinoid System (ECS): A Comprehensive Guide on Evidence-Based Interventions](https://aureamedicalsciencejournal.se/evidence-based-interventions-ecs-balance/): Dive deep into this comprehensive guide on how to optimize your endocannabinoid system (ECS). We delve into the science-backed interventions that could help you maintain the balance of your ECS. Enhance your health and well-being by understanding and influencing this crucial body system.
- [Tuning the Endocannabinoid System: Lifestyle Factors and Their Impact on ECS Tone](https://aureamedicalsciencejournal.se/tuning-the-endocannabinoid-system-lifestyle-factors-and-their-impact-on-ecs-tone/): Learn about the dynamic interplay between lifestyle habits and the Endocannabinoid System (ECS) tone. This comprehensive guide elaborates how physical exercise, dietary habits, stress, sleep, social interaction, and substance use can alter the ECS, potentially affecting mood, pain sensation, appetite, and more. Discover how understanding these interactions could shape future interventions and therapeutics.
- [Hidden in Plain Sight Part II – Umasking the ECS Connection in Common Drugs for Brain, Heart and Metabolic Disesases](https://aureamedicalsciencejournal.se/hidden-in-plain-sight-part-ii-umasking-the-ecs-connection-in-common-drugs-for-brain-heart-and-metabolic-disesases/): Unveiling the hidden role of the endocannabinoid system (ECS) in brain, heart, and metabolic health. Discover how non-cannabinoid drugs interact with the ECS, offering novel therapeutic insights and the potential for personalized treatment options. Explore the clinical significance and future directions of ECS modulation in drug development.
- [Hidden in Plain Sight: Unmasking the ECS Connection in Common Drugs for Pain Relief and Inflammation ](https://aureamedicalsciencejournal.se/hidden-in-plain-sight-unmasking-the-ecs-connection-in-common-drugs-for-pain-relief-and-inflammation/): Unmask the hidden interplay between the ECS/eCBome and common drugs used for brain, heart, and metabolic disorders. This article offers in-depth insights into the significance of the ECS/eCBome in health and disease, its interactions with major drug classes, and the future of therapeutic interventions leveraging this complex biological system.
- [The Endocannabinoid System and Parkinson's Disease: Therapeutic Insights and Perspectives](https://aureamedicalsciencejournal.se/the-endocannabinoid-system-and-parkinsons-disease-therapeutic-insights-and-perspectives/): Uncover the potential of the endocannabinoid system and the endocannabinoidome in Parkinson's disease management. This comprehensive review discusses current research and the promise of these systems for developing innovative treatment approaches to slow disease progression and alleviate symptoms.
- [The Upcoming Unavoidable Divergence of the Medical and Recreational Cannabis Markets](https://aureamedicalsciencejournal.se/the-upcoming-unavoidable-divergence-of-the-medical-and-recreational-cannabis-markets/): Gain insights into the growing divergence between recreational and medical cannabis markets as we explore the history, therapeutic potential, and challenges of medical cannabis. This in-depth article examines the endocannabinoid system, cannabinoids, medical uses, dosing, and legal status, all supported by an extensive list of references.
- [Adverse Effects of Too Much Cannabis](https://aureamedicalsciencejournal.se/adverse-effects-of-too-much-cannabis/): Delve into the adverse effects of excessive cannabis use with Aurea Care Medical Science Journal. From short-term memory impairment to potential long-term health risks, this article offers a detailed look at the potential dangers associated with irresponsible cannabis consumption and provides helpful strategies for harm reduction. Discover the importance of context, dosage, and cannabinoid formulation in both recreational and medical cannabis use.
- [The Unjustifiable Delay: Addressing the Absence of the Endocannabinoid System in Medical Textbooks and Education](https://aureamedicalsciencejournal.se/the-unjustifiable-delay-addressing-the-absence-of-the-endocannabinoid-system-in-medical-textbooks-and-education/): This article explores the critical need of integrating the endocannabinoid system (ECS) into medical education, highlighting the potential benefits for patient care and therapeutic progress. It addresses the consequences of delayed ECS education and calls for collective action to ensure its inclusion in medical curricula.
- [Cannabinoid Receptors and Neuroprotection: A Comprehensive Review of the Endocannabinoid System in the Brain](https://aureamedicalsciencejournal.se/cannabinoid-receptors-and-neuroprotection-a-comprehensive-review-of-the-endocannabinoid-system-in-the-brain/): Unravel the complexities of the Endocannabinoid System (ECS) and its neuroprotective mechanisms in the brain. Explore the function and distribution of cannabinoid receptors, the interplay with endogenous cannabinoids, and the potential neuroprotective benefits of THC and CBD. The article sheds light on potential future therapies targeting the ECS for preventing and treating neurological disorders.
- [Updated clinical guidelines for managing  chronic pain and co-occurring conditions with Cannabinoid-Based Medicines](https://aureamedicalsciencejournal.se/updated-clinical-guidelines-for-managing-chronic-pain-and-co-occurring-conditions-with-cannabinoid-based-medicines/): The article was published in March 2023 in the journal Cannabis and Cannabinoid Research. The research committee rated the strength of the recommendations and the quality of the evidence using the GRADE system. The guidelines provide updated practical recommendations for clinicians during a time period when approved conditions for CBMs vary substantially. The researchers emphasized the need for more high-quality research on the long-term effects and safety of CBMs for chronic pain and co-occurring conditio
- [Five arguments for, and one argument against, renaming the Endocannabinoid System](https://aureamedicalsciencejournal.se/five-arguments-for-and-one-argument-against-renaming-the-endocannabinoid-system/): This blog post argues for changing the name of the endocannabinoid system (ECS) to a more precise and comprehensive name that would better represent its natural and integral part of our biology. The post presents five reasons to consider changing the name and one reason to keep its current name. The post suggests that a new name for ECS would better reflect its diverse interactions with various molecules that happen within the ECS and would acknowledge its evolutionary origins and conservation.
- [The Missing Chapter: How Human Physiology Textbooks Fail to Include the Endocannabinoid System](https://aureamedicalsciencejournal.se/the-missing-chapter-how-human-physiology-textbooks-fail-to-include-the-endocannabinoid-system/): The article discusses the ECS and its importance in human physiology and medical education. It highlights the need to incorporate the ECS and its therapeutic potential into medical education and the challenges associated with the current lack of understanding and acceptance of the system among medical professionals and educators. The article provides examples from the ‘Guyton and Hall Textbook of Medical Physiology’ and a national survey conducted in 2017 to support its argument.
- [Can CBD reverse Type II Diabetes?](https://aureamedicalsciencejournal.se/can-cbd-reverse-type-ii-diabetes/): This article discusses the findings of a recent clinical trial that investigated the effects of a CBD/THC sublingual spray on glycemic control and lipid profiles in patients with Type II Diabetes. The study design, strengths, and weaknesses are discussed. The article highlights the significant improvements in cardiovascular biomarkers and glucose metabolism seen in the active treatment arm. It concludes by emphasizing the need for larger clinical studies to confirm and validate the results in larger patient populations.
- [The main reason behind most Doctors' reluctance to Medical Cannabis – and what needs to change.](https://aureamedicalsciencejournal.se/the-main-reason-behind-most-doctors-reluctance-to-medical-cannabis-and-what-needs-to-change/): This article discusses the importance of the endocannabinoid system (ECS) in mediating the effects of medical cannabis and the need for healthcare professionals to receive education and training on the ECS and its role in the body. It emphasizes the potential therapeutic benefits of medical cannabis for conditions such as chronic pain, anxiety, and inflammatory disorders. The article suggests that incorporating information about the ECS and medical cannabis into medical school curricula and providing ongoing education and training for healthcare professionals can help break down the stigma surrounding medical cannabis and improve patient outcomes.
- [Inside the World of Medical Cannabis: A Swedish Doctor's Perspective](https://aureamedicalsciencejournal.se/inside-the-world-of-medical-cannabis-a-swedish-doctors-perspective/): This article features an interview with Dr Orzala Pazhman, a Swedish physician working with medical cannabis. The interview discusses Dr Pazhman's experiences treating patients with medical cannabis, the current regulations for medical cannabis use in Sweden, and the need for more education around the endocannabinoid system in medical education.
- [In Memoriam - Dr. Raphael Mechoulam](https://aureamedicalsciencejournal.se/in-memoriam-dr-raphael-mechoulam/): In memoriam – Dr. Raphael Mechoulam. Explore the remarkable life and contributions of this pioneer in cannabinoid research and discover how his revolutionary work, including the isolation of THC and discovery of the ECS, has shaped modern medicine, neuroscience, and our understanding of cannabis. His profound impact on science and his legacy will continue to inspire future generations.
- [Medical Cannabis: Finding the Sweet Spot Between Therapeutic Benefits and Adverse Effects ](https://aureamedicalsciencejournal.se/medical-cannabis-finding-the-sweet-spot-between-therapeutic-benefits-and-adverse-effects/): Understanding medical cannabis's therapeutic potential necessitates a deep dive into its optimal dosage and administration. This article unravels the intricacies of determining the right dose, the challenges posed by individual variations, and the science behind the biphasic properties of cannabinoids. It also offers valuable guidelines for healthcare providers and calls for further research to establish standardized dosing.
- [Navigating the Benefits and Risks of CB1 Receptor Downregulation in Patients  on Long-Term Medical Cannabis Treatment](https://aureamedicalsciencejournal.se/navigating-the-benefits-and-risks-of-cb1-receptor-downregulation/): Dive into the world of medical cannabis and the endocannabinoid system. This article demystifies the implications of CB1 receptor downregulation in long-term medical cannabis users, discussing benefits like reduced cannabis tolerance and risks like cognitive impairment. Stay informed with the latest research and practical insights for healthcare professionals.
- [Munchies Meet Metabolism: How the Endocannabinoid System Responds to Diet](https://aureamedicalsciencejournal.se/munchies-meet-metabolism-how-the-endocannabinoid-system-responds-to-diet/): The article discusses the impact of diet on the endocannabinoid system (ECS) and its role in regulating metabolism, obesity, and metabolic disorders. It highlights the potential of dietary interventions and targeting the ECS as a therapeutic approach. The article provides information on the Mediterranean and Low-Carb High-Fat/ketogenic diets and the potential of CB1 receptor antagonists and inhibition of endocannabinoid metabolism enzymes as therapeutic strategies. The article emphasizes the need for further research to identify optimal dietary interventions and fully understand the complex interactions between dietary components and the ECS.
- [High on Relief: Exploring the Role of the Endocannabinoid System in Pain Management](https://aureamedicalsciencejournal.se/high-on-relief-exploring-the-role-of-the-endocannabinoid-system-in-pain-management/): Dive into the fascinating world of the Endocannabinoid System (ECS) and its influence on pain management. Uncover the role of CB1 and CB2 receptors, the significance of endocannabinoids like anandamide and 2-AG, and the effects of phytocannabinoids like THC and CBD. Understand the evidence supporting medical cannabis as a promising therapeutic strategy for chronic pain and various chronic conditions.

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# Detailed Content


## Pages

> This is an online scientific journal targeted towards the healthcare sector about the science of medical cannabis and the physiology of the endocannabinoid system.

- Published: 2025-07-10
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/patient-stories/
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> This is an online scientific journal targeted towards the healthcare sector about the science of medical cannabis and the physiology of the endocannabinoid system.

- Published: 2023-04-21
- Modified: 2023-04-21
- URL: https://aureamedicalsciencejournal.se/multimedia/
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> Sweden's first scientific magazine with a focus on everything about medical cannabis.

- Published: 2023-03-28
- Modified: 2023-03-28
- URL: https://aureamedicalsciencejournal.se/scientific-studies/
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> Sweden's first scientific magazine with a focus on everything about medical cannabis.

- Published: 2023-03-28
- Modified: 2023-03-28
- URL: https://aureamedicalsciencejournal.se/opinion-pieces/
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> Sweden's first scientific magazine with a focus on everything about medical cannabis.

- Published: 2023-03-19
- Modified: 2023-03-29
- URL: https://aureamedicalsciencejournal.se/interviews/
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> Sweden's first scientific magazine with a focus on everything about medical cannabis.

- Published: 2023-03-19
- Modified: 2023-03-19
- URL: https://aureamedicalsciencejournal.se/key-opinion-leaders-in-medical-cannabis/
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> Sweden's first scientific magazine with a focus on everything about medical cannabis.

- Published: 2023-02-28
- Modified: 2023-03-19
- URL: https://aureamedicalsciencejournal.se/educational-texts/
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> This is an online scientific journal targeted towards the healthcare sector about the science of medical cannabis and the physiology of the endocannabinoid system.

- Published: 2023-02-23
- Modified: 2024-02-29
- URL: https://aureamedicalsciencejournal.se/about-the-journal/
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- Published: 2023-01-13
- Modified: 2025-09-22
- URL: https://aureamedicalsciencejournal.se/
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- Published: 2023-01-13
- Modified: 2023-03-10
- URL: https://aureamedicalsciencejournal.se/privacy-policy/
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## Posts

- Published: 2025-10-02
- Modified: 2025-10-02
- URL: https://aureamedicalsciencejournal.se/what-stoners-and-buddhists-understood-before-neuroscientists/
- Categories: Opinion pieces
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- Published: 2025-09-22
- Modified: 2025-09-22
- URL: https://aureamedicalsciencejournal.se/the-philosophers-plant/
- Categories: Opinion pieces
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- Published: 2025-09-15
- Modified: 2025-09-15
- URL: https://aureamedicalsciencejournal.se/what-cannabis-teaches-us-about-reality/
- Categories: Opinion pieces
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- Published: 2025-09-01
- Modified: 2025-09-01
- URL: https://aureamedicalsciencejournal.se/the-war-on-consciousness/
- Categories: Opinion pieces
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- Published: 2025-08-25
- Modified: 2025-08-25
- URL: https://aureamedicalsciencejournal.se/what-cannabis-tells-us-about-medicine/
- Categories: Opinion pieces
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- Published: 2025-08-14
- Modified: 2025-08-14
- URL: https://aureamedicalsciencejournal.se/pain-is-not-just-a-signal-its-a-story/
- Categories: Opinion pieces
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- Published: 2025-07-21
- Modified: 2025-07-21
- URL: https://aureamedicalsciencejournal.se/medical-cannabis-and-polypharmacy-when-less-is-more/
- Categories: Opinion pieces
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- Published: 2025-07-11
- Modified: 2025-07-11
- URL: https://aureamedicalsciencejournal.se/cbd-thc-cbn-cbg-and-the-alphabet-soup-of-cannabinoids/
- Categories: Opinion pieces
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- Published: 2025-07-10
- Modified: 2025-07-11
- URL: https://aureamedicalsciencejournal.se/the-case-for-cannabis-in-complex-conditions/
- Categories: Opinion pieces
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- Published: 2025-06-26
- Modified: 2025-07-11
- URL: https://aureamedicalsciencejournal.se/the-endocannabinoid-system/
- Categories: Scientific Studies
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- Published: 2025-06-09
- Modified: 2025-07-11
- URL: https://aureamedicalsciencejournal.se/cannabis-isnt-a-cure-all-but-heres-what-it-does-really-well/
- Categories: Opinion pieces
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> Explore the intersection of cannabinoids and COVID-19 management, shedding light on the antiviral, immunomodulatory, and neuroprotective potentials of cannabinoids against SARS-CoV-2. Delve into the clinical implications, risks, and future prospects as we navigate through existing research towards a more efficacious therapeutic paradigm in combating this global pandemic.

- Published: 2023-10-18
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-role-of-cannabinoids-in-covid-19/
- Categories: Scientific Summaries
- Tags: Antiviral Therapies, Cannabinoids, Cannabis Pharmacology, Clinical Trials, COVID-19, Immunomodulation, Neuroprotection, SARS-CoV-2
This article delves into the rapidly growing realm of cannabinoids as potential therapeutic agents in managing COVID-19, engendered by SARS-CoV-2. By navigating through the antiviral and immunomodulatory properties of cannabinoids, the article seeks to provide a nuanced understanding of their potential impact on disease management, while elucidating the pivotal clinical and molecular mechanisms at play. The need for robust clinical trials and further research to corroborate these early insights is emphasized, heralding a call to action for the global scientific community.

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> Unveil the transformative impact of evidence-based education on public attitudes towards cannabis in Sinaloa, Mexico. Explore how demographic factors mediate the effectiveness of educational interventions and what this means for future drug policies. A must-read for anyone interested in the intersection of public health, policy, and social perceptions.

- Published: 2023-10-16
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/shifting-sands-of-perception-the-impact-of-evidence-based-education-on-cannabis-attitudes-in-sinaloa-mexico/
- Categories: Scientific Studies
- Tags: Cannabis Policy, Drug Regulation, Evidence-Based Education, Public Health, Research, Social Perception
Discover how an evidence-based educational intervention dramatically shifted public attitudes towards cannabis in Sinaloa, Mexico—a region historically entangled with repressive drug policies. This study highlights the transformative power of factual information and offers insights for policymakers and public health experts alike.

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> Dive deep into the symbiotic relationship between the Endocannabinoid System and PPARγ. Understand their roles in metabolism, inflammation, and potential as therapeutic targets. A must-read for healthcare professionals, pharmacologists, and researchers interested in metabolic and inflammatory disorders.

- Published: 2023-10-11
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/ecs-ppargamma-bidirectional-regulation/
- Categories: Scientific Summaries
- Tags: Endocannabinoid system, Inflammatory Response, Metabolic Regulation, molecular pharmacology, PPARγ, Signal Transduction, Therapeutic Implications, Transcriptional Regulation
Explore the intricate bidirectional relationship between the Endocannabinoid System (ECS) and Peroxisome Proliferator-Activated Receptor Gamma (PPARγ). This comprehensive review delves into their roles in metabolic and inflammatory regulation, molecular interactions, and emerging therapeutic possibilities.

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> Uncover the molecular dialogues between dietary omega fatty acids and the Homeostatic System. This comprehensive review highlights the pivotal role of omega fatty acids in modulating physiological processes, offering insights into potential therapeutic interventions and the importance of interdisciplinary collaboration in advancing nutritional therapeutics.

- Published: 2023-10-09
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/omega-fatty-acids-and-ecs/
- Categories: Scientific Summaries
- Tags: Disease Prevention, homeostatic system, molecular pharmacology, Nutrition, Omega Fatty Acids, Therapeutic Interventions
Explore the intricate interplay between dietary omega fatty acids and the Homeostatic System, and its implications for health and disease. Delve into how molecular pharmacology meets nutritional science to unfold promising avenues for disease prevention and management.

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> Dive into the intricate roles of the Endocannabinoid System (ECS) in regulating physiological homeostasis across diverse organ systems. Co-authored by two experts in the field, Stefan Broselid, Ph.D. and Sasha Weedowitch, BN, this article serves as an essential guide for healthcare providers, researchers, and educators, advocating for a more integrated ECS understanding in medical education and clinical practice.

- Published: 2023-09-29
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-homeostatic-system-effects-on-physiology/
- Categories: Opinion pieces, Scientific Summaries
- Tags: Emotional Regulation, Endocannabinoid system, medical education, Neuropharmacology, pain management, Personalized Medicine, Pharmacology, Physiological Homeostasis, Systems Biology, Therapeutic Interventions
This comprehensive article delves into the multifaceted roles of the Endocannabinoid System (ECS) in maintaining physiological homeostasis across multiple organ systems. From its influence on the nervous system and pain regulation to its complex interplay with metabolic and emotional regulation, the article argues for a broader integration of ECS understanding into medical education and personalized medicine.

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- Published: 2023-09-26
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/interview-amal-hagos/
- Categories: Interviews
- Tags: Endocannabinoid system, Ethical Considerations in Medicine, Evidence-based Practices, Healthcare Professional Interviews, medical cannabis, pain management
An enlightening discussion with Dr. Amal Hagos, a pain management specialist at Aurea Care in Stockholm, on the complexities and future of medical cannabis in treating chronic pain. This interview dives into evidence-based practices, the endocannabinoid system, ethical considerations, and much more.

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> Dive into an extensive review highlighting the intricate relationship between the Endocannabinoid System (ECS) and Autism Spectrum Disorders (ASD). Uncover key insights from in vivo models, clinical trials, and biomarker studies, shedding light on ECS dysfunction in ASD. This article aims to pave the way for future research and more effective, targeted treatments for ASD.

- Published: 2023-09-19
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/exploring-asd-and-ec-dysfunction/
- Categories: Scientific Summaries
- Tags: Autism Spectrum Disorders (ASD), Biomarkers in ASD, Clinical Research, Endocannabinoid System (ECS), In Vivo Models, Neuropsychiatric Disorders, Therapeutic Interventions
Explore the compelling links between the Endocannabinoid System (ECS) and Autism Spectrum Disorders (ASD). This in-depth review delves into genetic and chemically-induced in vivo models, ECS biomarkers in ASD, and the latest clinical research on ECS-targeted interventions. Understand the ECS's role as a potential therapeutic target and its broader implications for ASD pathology and treatment.

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> Unpacking the study "The Endocannabinoid Analgesic Entourage Effect," this article delves into the analgesic potential of endocannabinoids 2-AG, 2-PG, and 2-LG. Learn how these lipid-based signaling molecules influence TRPV1 receptor activation and offer new prospects for chronic pain management.

- Published: 2023-09-11
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/ecb-entourage-trpv1/
- Categories: Scientific Studies
- Tags: Cellular Research, Chronic Pain Management, Drug Development, endocannabinoids, neuropathic pain, Phytocannabinoids vs. Endocannabinoids
Discover groundbreaking research on the analgesic effects of endocannabinoids 2-AG, 2-PG, and 2-LG on TRPV1 receptors in cultured DRG neurons. This study provides invaluable insights into pain management and suggests novel avenues for drug development.

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> Dive into a groundbreaking umbrella review comparing the risks and benefits of cannabis. Utilizing the GRADE framework, this article provides a multi-faceted analysis that could reshape both clinical guidelines and public policy. Includes a detailed chart visualizing GRADE certainty levels

- Published: 2023-09-04
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/bmj-umbrella-review/
- Categories: Scientific Studies
- Tags: BMJ, cannabis research, Clinical Practice, GRADE Framework, Meta-Analyses, Policy and Legislation, Public Health
Explore the first-of-its-kind umbrella review, published in the prestigious BMJ, that synthesizes evidence on cannabis use through the lens of the GRADE framework. Understand the potential medical benefits, risks, and the societal implications of cannabis as compared to alcohol. This analysis serves as a cornerstone for clinicians, policymakers, and stakeholders.

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> "Decoding the Symphony: Genetic Variations in the ECS and Their Impact on Health" offers an in-depth analysis of the Endocannabinoid System's role in human physiology and its vulnerability to genetic mutations. The article provides an insightful look into how these genetic variations can influence behavior, disease prevalence, and pave the way for future therapeutic innovations. Ideal for healthcare professionals, researchers, and educators seeking a nuanced understanding of the ECS.

- Published: 2023-09-01
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/genetic-variations-in-ecs-impact-on-health/
- Categories: Scientific Summaries
- Tags: Behavioral Science, Clinical Research, Endocannabinoid system, Genetic Variations, Pharmacology, Physiology, Therapeutic Innovations
This comprehensive review delves into the genetic intricacies of the Endocannabinoid System (ECS) or Master Homeostatic Regulatory System (MHRS), illuminating its pivotal role in physiological homeostasis and its susceptibility to genetic mutations. By exploring the impact of these variations on behavior and disease, the article aims to serve as a foundation for future research and therapeutic developments in this burgeoning field.

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> Discover the pioneering work led by David “Dedi” Meiri that unveils the synergistic potential of three specific cannabinoids (331-18A, CBDV, and CBD) in battling NOTCH1-Mutated T-ALL. This comprehensive study, currently in preprint in BioRxIv, explores both in vitro and in vivo experiments to decode the 'entourage effect' in phytocannabinoids, laying a foundation for innovative cancer therapies and expanding our understanding of the Master Homeostatic Regulatory System (MHRS).

- Published: 2023-08-24
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/entourage-t-all/
- Categories: Scientific Studies
- Tags: Cancer Therapy, cannabis research, Integrated Stress Response Pathway, molecular pharmacology, NOTCH1-Mutated T-ALL, phytocannabinoids, Preclinical Research, Targeted Treatments
Investigating the synergistic effects of cannabinoids 331-18A, CBDV, and CBD, this groundbreaking study targets NOTCH1-Mutated T-Cell Lymphoblastic Acute Leukemia (T-ALL) through the Integrated Stress Response Pathway. By exploring the 'entourage effect' with a combination of specific phytocannabinoids, the research opens up new therapeutic horizons, shedding light on the intricate molecular interactions and their potential in cancer treatment.

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> "Dissecting the Acute Neurological Effects of THC" provides a comprehensive analysis of THC's acute effects on the brain. Drawing from resting state fMRI and genetic modulation, the study reveals how THC alters the brain's functionality, especially in individuals with specific genetic makeups. The findings extend our understanding of the endocannabinoid system's role in mental and dopaminergic health, opening new avenues for research and potential therapeutic applications.

- Published: 2023-08-22
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/thc-neurological-effects-genetics/
- Categories: Scientific Studies
- Tags: Cannabis Studies, Drug Development, Endocannabinoid system, Mental Health, Neurology, Pharmacology
This groundbreaking study explores the acute neurological effects of THC, focusing on functional connectivity, genetic modulation, physiological implications, and more. Uncover how THC impacts the brain's communication patterns, how specific genotypes react differently, and the broader context of these findings within the endocannabinoid system or Master Homeostatic Regulatory System (MHRS).

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> Unpacking Syed et al.'s groundbreaking 2023 study on physicians' perspectives of medical cannabis. Explore international insights, knowledge gaps, and the call for a more informed medical community on the use and potential of cannabis in treatment.

- Published: 2023-08-16
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/international-physicians-perspective-medical-cannabis-2023-study/
- Categories: Scientific Studies
- Tags: Global Health Perspectives, homeostatic system, medical cannabis, Medical Education & Training, Medical Guidelines & Recommendations, Physician Studies, therapeutic potential
In a revealing international survey, Syed et al. delve into the knowledge, attitudes, and practices of physicians regarding medical cannabis. With responses from 17 countries, the study uncovers significant gaps in understanding and highlights the urgent need for enhanced medical education on this topic.

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> Discover the field of endocannabinology and its focus on the endocannabinoid system (ECS) for maintaining mental and physical health. Learn how the 'endocannabinology approach' differs from a 'medical cannabis approach'. Gain insights into integrating endocannabinology into mental health nursing. Read this insightful interview for a comprehensive understanding of endocannabinology.

- Published: 2023-07-24
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/endocannabinology-interview/
- Categories: Interviews
- Tags: Arachidonic acid, diet, Endocannabinoid system, endocannabinoids, endocannabinology, homeostatic system, Homeostatica, Lifestyle, Mental Health, Mental Nurse, Omega 3, Omega 6, Supplements
Explore the fascinating field of endocannabinology and its impact on mental and physical health. Learn about the differences between the 'endocannabinology approach' and a 'medical cannabis approach' and discover the importance of lifestyle interventions in maintaining balance. Gain insights into integrating endocannabinology into mental health nursing and monitoring patient progress. Stay updated with the latest research and debunk misconceptions about the endocannabinoid system. Read this insightful interview with Sasha Vidovic, Mental Nurse, to learn into the world of endocannabinology

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> Join the pivotal conversation on medical cannabis at the Stockholm Medical Cannabis Conference. Explore diverse topics surrounding the potential benefits of cannabis, patient narratives, and the impact of shifting from punitive to harm reduction strategies. Be part of the solution in Sweden's escalating drug crisis.

- Published: 2023-07-10
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/smcc2023/
- Categories: Opinion pieces
- Tags: Harm Reduction Strategies, Healthcare Events, Integrated Healthcare, medical cannabis, medical education, Social Issues in Sweden, Swedish Drug Policy
The Stockholm Medical Cannabis Conference, organized by Aureum Life, aims to challenge Sweden's stringent drug policies amidst an escalating crisis. With an emphasis on education and open dialogue, the conference is a potential pivot point, opening up pathways for a new understanding of the therapeutic potential of cannabis.

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> Dive into the realm of topical cannabinoids and their applications in treating various skin conditions and managing pain. This in-depth review unravels the scientific evidence, market availability, regulatory status, and future prospects of these potent compounds. Equip yourself with the latest knowledge and stay at the forefront of this promising pharmacological field.

- Published: 2023-06-28
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/navigating-the-world-of-topical-cannabinoids/
- Categories: Scientific Summaries
- Tags: Alternative Therapies, Dermatology, Medical Research, pain management
Explore the burgeoning world of topical cannabinoids and their potential roles in dermatology and pain management. Discover the regulatory landscape, commercially available products, promising research, and future implications in this comprehensive overview.

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> Dive into the world of medical cannabis and the controversial 'high' it induces. This article, grounded in recent research, challenges the notion that the 'high' is an unwanted side effect, suggesting instead that it may be a separate phenomenon that doesn't hinder the therapeutic potential of cannabis.

- Published: 2023-06-19
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/rethinking-cannabis-high-therapeutic-potential/
- Categories: Scientific Studies
- Tags: feeling high, Health and Wellness, medical cannabis, THC, therapeutic outcomes
Explore the nuanced understanding of the 'high' associated with medical cannabis use. This article, based on a recent study, challenges traditional perceptions and invites readers to consider the 'high' as a separate phenomenon that may not interfere with the therapeutic benefits of cannabis.

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> Unlock the potential of nanotechnology in revolutionizing cannabinoid delivery. Learn how nanoencapsulation can optimize pharmacokinetic and pharmacodynamic properties, mitigate challenges, and expand the therapeutic potential of cannabinoids. A must-read for anyone interested in the intersection of molecular pharmacology and nanotechnology.

- Published: 2023-06-15
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/nanotechnology-enhanced-cannabinoid-delivery/
- Categories: Scientific Summaries
- Tags: Cannabinoids, Drug Delivery, molecular pharmacology, Nanotechnology
This article explores the role of nanotechnology in improving the delivery and efficacy of cannabinoids. By focusing on nanoencapsulation techniques such as liposomes and polymeric nanoparticles, we delve into how these methods can enhance bioavailability, stability, and therapeutic efficacy of cannabinoids, thereby offering significant advancements in molecular pharmacology.

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- Published: 2023-06-14
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/is-cbd-effective-against-more-than-epilepsy/
- Categories: Scientific Studies
- Tags: Autism, Cannabidiol (CBD), Clinical Studies, Evidence-Based Medicine, Graft-versus-Host Disease, Intestinal Permeability, Medical Research, Mental Health, Neurological Disorders, Parkinson's disease, Randomized Controlled Trials, Sleep Disorders, Substance Abuse, therapeutic potential
In this blog post, we provide a summary of a recent review article published in the Journal of Cannabis Research by O'Sullivan et al. on June 13th. The review focuses on the use of purified CBD products in clinical studies to determine potential indications for which purified CBD could be beneficial. While the findings suggest that purified CBD can be effective in various conditions beyond epilepsy, the evidence base is limited due to trials primarily investigating acute effects, trials conducted on healthy volunteers, and trials with small patient populations. To establish the efficacy of purified CBD across different indications, large confirmatory phase 3 trials are necessary. Join us as we delve into the therapeutic benefits of purified CBD for various conditions based on randomized controlled trials and explore the strengths and weaknesses of the review.

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> Delve into the captivating Gut-Brain-Bliss Connection and unravel the intricate relationship between the gut microbiota, endocannabinoid system, and overall well-being. Discover the potential implications for neurological disorders, mental health, and personalized therapeutic interventions. Explore the forefront of health research with this thought-provoking article.

- Published: 2023-06-09
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-gut-brain-bliss-connection/
- Categories: Scientific Summaries
- Tags: Endocannabinoid system, Gut Health, Health, Mental Health, Neuroscience
Explore the fascinating connection between the gut, brain, and bliss in this insightful article. Discover how the gut microbiota and the endocannabinoid system influence brain function, mood, and overall health. Gain insights into the potential therapeutic approaches and the exciting possibilities for personalized medicine in this emerging field of research.

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> Uncover the significant role of non-GPCR targets within the endocannabinoid system. With a keen focus on FAAH, MAGL, DAGL, NAPE-PLD, TRP channels, and PPARs, this comprehensive review provides insights into their implications in a spectrum of human pathologies, including neuropsychiatric, metabolic, and neurological disorders. A valuable resource for medical professionals and researchers alike.

- Published: 2023-06-08
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/non-gpcr-targets-in-the-ecbome/
- Categories: Scientific Summaries
- Tags: DAGL, Endocannabinoid system, FAAH, MAGL, metabolic disorders, NAPE-PLD, Neurological Disorders, Neuropsychiatric Disorders, Non-GPCR Targets, PPARs, Therapeutic Intervention, TRP Channels
Delve into the lesser-known facets of the endocannabinoid system (eCBome), focusing on non-GPCR targets like FAAH, MAGL, DAGL, NAPE-PLD, TRP channels, and PPARs. Discover their critical roles in human physiology and their potential for therapeutic intervention in neuropsychiatric, metabolic, and neurological disorders.

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> Explore the fascinating interplay between synucleins and endocannabinoids in Parkinson's disease (PD). This article summarizes the key findings of a recent study published in Nature Neuroscience, offering insights into the potential therapeutic role of phytocannabinoids in PD. Dive into the world of molecular pharmacology and neuroscience as we unravel new findings related to Parkinson's disease.

- Published: 2023-06-01
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/synuclein-synchrony/
- Categories: Scientific Studies
- Tags: Endocannabinoid Signaling, molecular pharmacology, Neuroscience, Parkinson's Disease Research, Synucleins
In the groundbreaking study "Postsynaptic Synucleins Mediate Endocannabinoid Signaling," Eddy Albarran and colleagues delve into the intricate dance between synucleins and endocannabinoids within postsynaptic neurons. Their findings shed light on the potential role of phytocannabinoids in alleviating symptoms of Parkinson's disease, offering a fresh perspective on therapeutic strategies

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> Dive into the world of eCBome GPCRs with this comprehensive review. Discover the intricate roles of different receptors in the endocannabinoid system and their links to various diseases. Uncover the future potential of this fascinating area in therapeutic interventions and novel research directions. A must-read for anyone interested in neuroscience, pharmacology, and the future of personalised medicine.

- Published: 2023-05-31
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/deciphering-the-ecbome-enigma/
- Categories: Scientific Summaries
- Tags: Disease Pathologies, eCBome, Endocannabinoid system, G-protein Coupled Receptors, GPCR, homeostatic system, Human Physiology, Neuroscience, Pharmacology, Therapeutic Interventions
Explore the fascinating interplay between the endocannabinoid system and G-protein Coupled Receptors (GPCRs), as we delve into the implications of eCBome GPCRs in human physiology and disease pathologies. Learn about how these receptors contribute to crucial functions such as appetite regulation, immune responses, and cognition, and understand their significant roles in conditions ranging from obesity to neurodevelopmental disorders.

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> Dive into the world of epigenetics and learn about the profound impact of substance use on DNA methylation. Explore a detailed study investigating the effects of tobacco, alcohol, and cannabis on our genetic 'algorithm'. Understand the implications of these findings on health outcomes and appreciate the need for further research in the field. Informed decisions today can lead to better health tomorrow.

- Published: 2023-05-25
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/tobacco-alcohol-cannabis-dna-methylation-effects-health/
- Categories: Scientific Studies
- Tags: Alcohol, cannabis, DNA methylation, Epigenetic modification, epigenetics, Gene regulation, Health effects, Health research, Substance use, Tobacco
Unravel the science behind the influence of tobacco, alcohol, and cannabis on our DNA. Dive into the impact of these substances on DNA methylation and learn how these lifestyle choices can modify gene activity, potentially affecting health outcomes.

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> This article reviews a study published in JAMA Network Open by Arkell et al., exploring the potential benefits of medical cannabis on health-related quality of life. Particularly, it suggests that medical cannabis may help improve quality of life for patients with chronic pain, with CBD-dominant products showing promising results.

- Published: 2023-05-17
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/medical-cannabis-improves-quality-of-life-study-review/
- Categories: Scientific Studies
- Tags: cannabis for chronic conditions, cannabis for pain management, cannabis treatment, CBD-dominant cannabis, chronic pain, health-related quality of life, JAMA Network Open study, medical cannabis, medical cannabis study, SF-36 health survey, THC-dominant cannabis
Exploring the impact of medical cannabis on health-related quality of life, this review delves into the Arkell et al. study in JAMA Network Open. With a focus on chronic pain patients, the research points to significant improvements across various health domains. Particularly, CBD-dominant cannabis products show promising results. Discover the key findings, strengths, and weaknesses of this impactful study.

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> Dive deep into this comprehensive guide on how to optimize your endocannabinoid system (ECS). We delve into the science-backed interventions that could help you maintain the balance of your ECS. Enhance your health and well-being by understanding and influencing this crucial body system.

- Published: 2023-05-16
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/evidence-based-interventions-ecs-balance/
- Categories: Scientific Summaries
- Tags: ECS, Endocannabinoid system, Health and Wellness, Intermittent Fasting, Ketogenic Diet, Medical Interventions, Mediterranean diet, Nutritional Supplements, omega-3 fatty acids, Physical Activity, Sleep Hygiene, Social Interactions, Stress Management
Discover the secrets of balancing your body's endocannabinoid system (ECS) through various evidence-based interventions. Uncover the influence of dietary choices, exercise routines, stress management techniques, and more on the ECS. This comprehensive guide provides insights on how to optimize your ECS and enhance your overall well-being.

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> Learn about the dynamic interplay between lifestyle habits and the Endocannabinoid System (ECS) tone. This comprehensive guide elaborates how physical exercise, dietary habits, stress, sleep, social interaction, and substance use can alter the ECS, potentially affecting mood, pain sensation, appetite, and more. Discover how understanding these interactions could shape future interventions and therapeutics.

- Published: 2023-05-14
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/tuning-the-endocannabinoid-system-lifestyle-factors-and-their-impact-on-ecs-tone/
- Categories: Scientific Summaries
- Tags: Alcohol and Substance Use, diet, ECS tone, ECS-based treatments, Endocannabinoid system, Lifestyle Factors, omega-3 fatty acids, Physical Activity, Social Interaction, Stress and Sleep
Uncover how lifestyle factors like physical activity, diet, stress, sleep, social interaction, and substance use influence the Endocannabinoid System (ECS) tone. This article examines the role of ECS, a complex biological system, in maintaining bodily homeostasis and how different behaviors can modulate it, with potential implications for health and disease.

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> Unveiling the hidden role of the endocannabinoid system (ECS) in brain, heart, and metabolic health. Discover how non-cannabinoid drugs interact with the ECS, offering novel therapeutic insights and the potential for personalized treatment options. Explore the clinical significance and future directions of ECS modulation in drug development.

- Published: 2023-05-12
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/hidden-in-plain-sight-part-ii-umasking-the-ecs-connection-in-common-drugs-for-brain-heart-and-metabolic-disesases/
- Categories: Scientific Summaries
- Tags: eCBome, ECS connection in common drugs, Endocannabinoid system, Endocannabinoid system interactions, Molecular interactions with ECS/eCBome, Novel therapeutics targeting ECS
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> Unmask the hidden interplay between the ECS/eCBome and common drugs used for brain, heart, and metabolic disorders. This article offers in-depth insights into the significance of the ECS/eCBome in health and disease, its interactions with major drug classes, and the future of therapeutic interventions leveraging this complex biological system.

- Published: 2023-05-06
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/hidden-in-plain-sight-unmasking-the-ecs-connection-in-common-drugs-for-pain-relief-and-inflammation/
- Categories: Scientific Summaries
- Tags: acetaminophen, eCBome, ECS, Inflammation, non-cannabinoid drugs, NSAIDs, Opioids, pain relief, paracetamol
SEO Excerpt:
"Discover the vital connections between common pain relief and anti-inflammatory drugs with the endocannabinoid system (ECS) and endocannabinoidome (eCBome). Learn how acetaminophen, NSAIDs, and opioid analgesics interact with these systems and understand the implications for novel, more effective treatments.

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> Uncover the potential of the endocannabinoid system and the endocannabinoidome in Parkinson's disease management. This comprehensive review discusses current research and the promise of these systems for developing innovative treatment approaches to slow disease progression and alleviate symptoms.

- Published: 2023-04-29
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-endocannabinoid-system-and-parkinsons-disease-therapeutic-insights-and-perspectives/
- Categories: Scientific Summaries
- Tags: CB1 receptors, CB2 receptors, eCBome, Endocannabinoid system, N-oleoylglycine, Neurodegenerative diseases, Parkinson's disease, therapeutic potential
Explore the intricate connection between the endocannabinoid system (ECS), its expanded version - the endocannabinoidome (eCBome), and Parkinson's disease (PD). The article delves into the potential of these systems as novel therapeutic targets for PD, offering fresh insights into ongoing research and future treatment possibilities.

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> Gain insights into the growing divergence between recreational and medical cannabis markets as we explore the history, therapeutic potential, and challenges of medical cannabis. This in-depth article examines the endocannabinoid system, cannabinoids, medical uses, dosing, and legal status, all supported by an extensive list of references.

- Published: 2023-04-19
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-upcoming-unavoidable-divergence-of-the-medical-and-recreational-cannabis-markets/
- Categories: Opinion pieces
- Tags: Cannabinoids, cannabis for pain relief, cannabis legalization, Endocannabinoid system, medical cannabis, medical cannabis dosing, medical marijuana, therapeutic benefits
Medical and recreational cannabis markets are likely to diverge further as scientific research reveals more therapeutic benefits of cannabis and its derivatives. This divergence stems from the demand for specific, evidence-based treatments for various medical conditions, which require accurate dosing, controlled formulations, and strict quality standards. On the other hand, recreational cannabis products are mainly designed for consumer satisfaction and preferences, with a wider range of product types and a continuous focus on THC potencies.

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> Delve into the adverse effects of excessive cannabis use with Aurea Care Medical Science Journal. From short-term memory impairment to potential long-term health risks, this article offers a detailed look at the potential dangers associated with irresponsible cannabis consumption and provides helpful strategies for harm reduction. Discover the importance of context, dosage, and cannabinoid formulation in both recreational and medical cannabis use.

- Published: 2023-04-14
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/adverse-effects-of-too-much-cannabis/
- Categories: Scientific Summaries
- Tags: adverse effects, cannabis, Cannabis Hyperemesis Syndrome, CMS, drug interactions, edibles, medical cannabis, tolerance
Explore the potential risks of excessive cannabis use, from short-term to long-term effects, with our comprehensive overview. Learn about the impact of THC and CBD concentrations in different cannabis chemovars, the dangers of large oral doses and edibles, and strategies for reducing these risks through responsible use and education.

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> This article explores the critical need of integrating the endocannabinoid system (ECS) into medical education, highlighting the potential benefits for patient care and therapeutic progress. It addresses the consequences of delayed ECS education and calls for collective action to ensure its inclusion in medical curricula.

- Published: 2023-04-06
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-unjustifiable-delay-addressing-the-absence-of-the-endocannabinoid-system-in-medical-textbooks-and-education/
- Categories: Opinion pieces
- Tags: cannabinoid medicine, ECS in healthcare, Endocannabinoid system, medical cannabis, medical curricula, medical education, patient care
In conclusion, the bibliographic analysis and table strongly implies that the ECS is an important area of research with a considerable impact on the scientific community. Despite the relatively lower number of publications compared to some other physiological systems, the high total citations and h-index for the ECS demonstrate its relevance and significance. The exclusion of the ECS from medical textbooks and education is therefore not only unprecedented but also unacceptable, given its importance in human physiology.

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> Unravel the complexities of the Endocannabinoid System (ECS) and its neuroprotective mechanisms in the brain. Explore the function and distribution of cannabinoid receptors, the interplay with endogenous cannabinoids, and the potential neuroprotective benefits of THC and CBD. The article sheds light on potential future therapies targeting the ECS for preventing and treating neurological disorders.

- Published: 2023-04-04
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/cannabinoid-receptors-and-neuroprotection-a-comprehensive-review-of-the-endocannabinoid-system-in-the-brain/
- Categories: Scientific Summaries
- Tags: cannabinoid receptors, CB1 receptors, CB2 receptors, CBD, Endocannabinoid system, neuroinflammation, Neuroprotection, TBI, THC, traumatic brain injury
Delve into the neuroprotective role of the Endocannabinoid System (ECS) in the brain, with particular emphasis on CB1 and CB2 cannabinoid receptors. This comprehensive review covers the ECS’s crucial role in neuronal protection against trauma, ischemia, neuroinflammation, and neurodegeneration. Additionally, learn about the potential therapeutic implications of various endogenous neuroprotective compounds that interact with the ECS.

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> The article was published in March 2023 in the journal Cannabis and Cannabinoid Research. The research committee rated the strength of the recommendations and the quality of the evidence using the GRADE system. The guidelines provide updated practical recommendations for clinicians during a time period when approved conditions for CBMs vary substantially. The researchers emphasized the need for more high-quality research on the long-term effects and safety of CBMs for chronic pain and co-occurring conditio

- Published: 2023-03-31
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/updated-clinical-guidelines-for-managing-chronic-pain-and-co-occurring-conditions-with-cannabinoid-based-medicines/
- Categories: Scientific Studies
- Tags: adverse events, cannabinoid-based medicines, cannabis guidelines, chronic pain, clinical guidelines, clinical recommendations, dosing, medical cannabis, medical marijuana, monitoring, neuropathic pain, patient education, systematic review
Researchers conducted a systematic review of studies investigating the use of cannabinoid-based medicines (CBMs) for chronic pain management and developed clinical practice guidelines based on the evidence. The review found that CBMs may provide benefits for chronic pain reduction, especially for neuropathic pain, and help with some co-occurring conditions. However, CBMs may cause some adverse events, and the optimal use of CBMs for chronic pain and co-occurring conditions is not clear. The guidelines provide practical recommendations for clinicians on patient education, assessment, dosing, administration routes, monitoring, and discontinuation of CBMs.

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> This blog post argues for changing the name of the endocannabinoid system (ECS) to a more precise and comprehensive name that would better represent its natural and integral part of our biology. The post presents five reasons to consider changing the name and one reason to keep its current name. The post suggests that a new name for ECS would better reflect its diverse interactions with various molecules that happen within the ECS and would acknowledge its evolutionary origins and conservation.

- Published: 2023-03-28
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/five-arguments-for-and-one-argument-against-renaming-the-endocannabinoid-system/
- Categories: Opinion pieces
- Tags: ECS, Endocannabinoid system, homeostatic system, medical education, medical relevance, natural biology, stigma, therapeutic applications
In this blog post, the author presents five reasons to consider changing the name of the endocannabinoid system (ECS) and one reason to keep its current name. The author argues that the name of the ECS does not accurately represent its natural and integral part of our biology. The name limits our understanding of its potential therapeutic applications, ignores its complexity and diversity of components, and hinders its public acceptance and incorporation into medical education. The author suggests a more precise and comprehensive name that would better represent the diverse interactions that happen within the ECS.

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> The article discusses the ECS and its importance in human physiology and medical education. It highlights the need to incorporate the ECS and its therapeutic potential into medical education and the challenges associated with the current lack of understanding and acceptance of the system among medical professionals and educators. The article provides examples from the ‘Guyton and Hall Textbook of Medical Physiology’ and a national survey conducted in 2017 to support its argument.

- Published: 2023-03-27
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-missing-chapter-how-human-physiology-textbooks-fail-to-include-the-endocannabinoid-system/
- Categories: Opinion pieces
- Tags: cb1, CB2, ECS, ECS components, Endocannabinoid system, homeostasis, medical cannabis, medical education, medical schools, physiology textbooks, stigma, therapeutic potential
The endocannabinoid system (ECS) is a complex network of receptors, ligands, and enzymes that modulates various physiological processes in the human body. However, despite its critical role in human health and disease, the ECS and its components have not been adequately included in many popular medical textbooks, such as the ‘Guyton and Hall Textbook of Medical Physiology’. This article highlights the importance of incorporating the ECS and its therapeutic potential into medical education, as most doctors are not trained in the ECS and consequently have inadequate knowledge about the potential therapeutic uses of medical cannabis.

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> This article discusses the findings of a recent clinical trial that investigated the effects of a CBD/THC sublingual spray on glycemic control and lipid profiles in patients with Type II Diabetes. The study design, strengths, and weaknesses are discussed. The article highlights the significant improvements in cardiovascular biomarkers and glucose metabolism seen in the active treatment arm. It concludes by emphasizing the need for larger clinical studies to confirm and validate the results in larger patient populations.

- Published: 2023-03-22
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/can-cbd-reverse-type-ii-diabetes/
- Categories: Scientific Studies
- Tags: Cannabidiol, CBD, CBDEX10, clinical trial, Diabetes, glycemic control, lipid profiles, metabolic syndrome, sublingual spray, T2D, Type 2 Diabetes, Type II diabetes
A phase I double-blind placebo-controlled clinical trial examined the effects of a 10:1 CBD/THC sublingual spray in improving glycemic control and lipid profiles in patients with Type II Diabetes. The study involved 50 patients, 25 of whom were given a 200 mg/20 mg CBD/Δ9-THC sublingual spray twice daily for eight weeks, while the other 25 were given a placebo. The study found that the active treatment arm showed significant improvements in various biomarkers related to cardiovascular health and glucose metabolism. The results suggest that adjunctive treatment with sublingual CBD/Δ9-THC can improve glycemic control and lipid profiles in patients with Type II Diabetes.

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> This article discusses the importance of the endocannabinoid system (ECS) in mediating the effects of medical cannabis and the need for healthcare professionals to receive education and training on the ECS and its role in the body. It emphasizes the potential therapeutic benefits of medical cannabis for conditions such as chronic pain, anxiety, and inflammatory disorders. The article suggests that incorporating information about the ECS and medical cannabis into medical school curricula and providing ongoing education and training for healthcare professionals can help break down the stigma surrounding medical cannabis and improve patient outcomes.

- Published: 2023-03-21
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/the-main-reason-behind-most-doctors-reluctance-to-medical-cannabis-and-what-needs-to-change/
- Categories: Opinion pieces
- Tags: ECS, education, Endocannabinoid system, healthcare professionals, medical cannabis, medical education, medical school, medical school curricula, therapeutic benefits, training
Despite the growing acceptance of medical cannabis among the public, most doctors remain reluctant to recommend it to their patients due to a lack of understanding of the endocannabinoid system (ECS) and the role it plays in mediating the effects of cannabis in the body. The ECS is a complex regulatory system that plays a fundamental role in regulating a wide range of physiological processes, including appetite, pain sensation, mood, and immune function. Medical schools and universities should incorporate information about the ECS and medical cannabis into their curricula, and healthcare professionals should receive ongoing education and training to stay up-to-date with the latest research and prescribing guidelines.

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> This article features an interview with Dr Orzala Pazhman, a Swedish physician working with medical cannabis. The interview discusses Dr Pazhman's experiences treating patients with medical cannabis, the current regulations for medical cannabis use in Sweden, and the need for more education around the endocannabinoid system in medical education.

- Published: 2023-03-19
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/inside-the-world-of-medical-cannabis-a-swedish-doctors-perspective/
- Categories: Interviews
- Tags: chronic pain, Endocannabinoid system, epilepsy, medical cannabis, medical education, multiple sclerosis, neuropathic pain, Swedish regulations
Dive into the world of medical cannabis from a Swedish physician's perspective. Dr. Orzala Pazhman shares her insights on treating chronic pain with cannabis-based medicines and discusses the future of medical cannabis in Sweden.

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> In memoriam – Dr. Raphael Mechoulam. Explore the remarkable life and contributions of this pioneer in cannabinoid research and discover how his revolutionary work, including the isolation of THC and discovery of the ECS, has shaped modern medicine, neuroscience, and our understanding of cannabis. His profound impact on science and his legacy will continue to inspire future generations.

- Published: 2023-03-17
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/in-memoriam-dr-raphael-mechoulam/
- Categories: KOLs in Medical Cannabis
- Tags: anandamide, cannabinoid research, Cannabis science, CBDA-ME, Dr. Raphael Mechoulam, Endocannabinoid system, molecular pharmacology, THC, therapeutic potential of cannabis
Celebrating the life and legacy of Dr. Raphael Mechoulam, a pioneering scientist in the fields of molecular pharmacology and cannabinoid research. His groundbreaking work on the endocannabinoid system (ECS) has transformed our understanding of human physiology and medical science.

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> Understanding medical cannabis's therapeutic potential necessitates a deep dive into its optimal dosage and administration. This article unravels the intricacies of determining the right dose, the challenges posed by individual variations, and the science behind the biphasic properties of cannabinoids. It also offers valuable guidelines for healthcare providers and calls for further research to establish standardized dosing.

- Published: 2023-03-15
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/medical-cannabis-finding-the-sweet-spot-between-therapeutic-benefits-and-adverse-effects/
- Categories: Scientific Summaries
- Tags: administration, adverse effects, atient assessment, cannabis dosing guidelines, dosing, healthcare providers, medical cannabis, medical cannabis dosing guidelines, medical marijuana dosing guidelines, pharmacokinetics, therapeutic benefits
Explore the complexities of finding the optimal dosage and administration of medical cannabis. This comprehensive review dives into various factors such as the individual’s medical condition, age, and genetics, the plant's biphasic properties, and the need for standardized quality-controlled products. Discover the balance between maximizing therapeutic benefits while minimizing potential adverse effects.

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> Dive into the world of medical cannabis and the endocannabinoid system. This article demystifies the implications of CB1 receptor downregulation in long-term medical cannabis users, discussing benefits like reduced cannabis tolerance and risks like cognitive impairment. Stay informed with the latest research and practical insights for healthcare professionals.

- Published: 2023-03-12
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/navigating-the-benefits-and-risks-of-cb1-receptor-downregulation/
- Categories: Scientific Summaries
- Tags: cannabis tolerance, cb1, chronic cannabis consumption, chronic pain, Endocannabinoid system, medical cannabis, receptor downregulation
Explore the complex dynamics of CB1 receptor downregulation in patients on long-term medical cannabis treatment. We unravel both potential benefits and risks of this phenomenon, impacting therapeutic efficacy and side effects. Essential reading for healthcare professionals prescribing medical cannabis.

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> The article discusses the impact of diet on the endocannabinoid system (ECS) and its role in regulating metabolism, obesity, and metabolic disorders. It highlights the potential of dietary interventions and targeting the ECS as a therapeutic approach. The article provides information on the Mediterranean and Low-Carb High-Fat/ketogenic diets and the potential of CB1 receptor antagonists and inhibition of endocannabinoid metabolism enzymes as therapeutic strategies. The article emphasizes the need for further research to identify optimal dietary interventions and fully understand the complex interactions between dietary components and the ECS.

- Published: 2023-03-06
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/munchies-meet-metabolism-how-the-endocannabinoid-system-responds-to-diet/
- Categories: Scientific Summaries
- Tags: cannabinoid receptors, CB1 receptor antagonists, diet, Endocannabinoid system, endocannabinology, fiber, fructose, insulin sensitivity, Low-Carb High-Fat diet, Mediterranean diet, metabolic disorders, metabolic health, metabolism, obesity, omega-3 fatty acids
Explore the fascinating relationship between the endocannabinoid system (ECS) and diet. Understand how dietary components like omega-3 fatty acids and fiber influence the ECS, and the implications this holds for obesity and metabolic disorders. The ECS represents a promising therapeutic target for metabolic disorders, shedding light on the intricate ties between our diet and overall health.

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> Dive into the fascinating world of the Endocannabinoid System (ECS) and its influence on pain management. Uncover the role of CB1 and CB2 receptors, the significance of endocannabinoids like anandamide and 2-AG, and the effects of phytocannabinoids like THC and CBD. Understand the evidence supporting medical cannabis as a promising therapeutic strategy for chronic pain and various chronic conditions.

- Published: 2023-02-28
- Modified: 2025-07-10
- URL: https://aureamedicalsciencejournal.se/high-on-relief-exploring-the-role-of-the-endocannabinoid-system-in-pain-management/
- Categories: Scientific Summaries
- Tags: CB1 receptor, CB2 receptor, chronic pain, Endocannabinoid system, endocannabinoids, medical cannabis, pain management, phytocannabinoids, retrograde signaling
Explore the intricate role of the Endocannabinoid System (ECS) in pain management. This article unravels the complex network of the ECS, its regulatory function in pain modulation, the implications of endocannabinoids and phytocannabinoids, and the potential of medical cannabis in managing chronic pain and other medical conditions. Learn how the ECS plays a crucial part in maintaining homeostasis, reducing inflammation, and regulating pain perception.

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